RSS Feed

Diacerein Description

Diacerein is a diacetyl forerunner of rhein, an anthraquinone begin in plants. Rhein, at 10 µM, inhibits IL-1β signaling, suppressing signaling through NF-κB and AP-1, and reduces the announcement of the cast metalloproteases MMP-1 and MMP-13. Diacerein, apparently afterwards about-face to rhein, down-regulates the announcement of the IL-1β receptor on articular chondrocytes, enhances the announcement of TGF-β, and increases collagen and aggrecan. It does not adapt COX activity. It is agilely able in ameliorating osteoarthritis.

Advertisements

About Chemicals company

where to buy chemical online? BuyChemical.net - chemistry chemicals Manufacturers, chemicals Importer,Suppliers of Chemicals on KFO.KFO is a Chemicals company

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: