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What is Calcifediol?

Calcifediol (INN), aswell accepted as calcidiol, 25-hydroxycholecalciferol, or 25-hydroxyvitamin D (abbreviated 25(OH)D), is a prehormone that is produced in the alarmist by hydroxylation of vitamin D3 (cholecalciferol) by the agitator cholecalciferol 25-hydroxylase which was abandoned by Michael F. Holick. Physicians common admeasurement this metabolite to actuate a patient’s vitamin D status. At a archetypal circadian assimilation of vitamin D3, its abounding about-face to calcifediol takes about 7 days.

Calcifediol is again adapted in the kidneys (by the agitator 25(OH)D-1α-hydroxylase) into calcitriol (1,25-(OH)2D3), a secosteroid hormone that is the alive anatomy of vitamin D. It can aswell be adapted into 24-hydroxycalcidiol in the kidneys via 24-hydroxylation.


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